Atrin Pharmaceuticals is a private biopharmaceutical company pioneering the discovery & development of proprietary molecules targeting DNA Damage and Response (DDR) pathways to treat a broad range of cancers associated with deregulated DNA Damage Response.
Atrin’s scientific founders were the first to discover the key role of the Ataxia Telangiectasia and Rad3-related (ATR) pathway in treating cancers.
The emerging role of DDR treatments in cancer is expected to represent a cornerstone in novel targeted monotherapy and combination anticancer therapies. Atrin’s lead ATR molecules are projected to become best-in-class DDR inhibitors.
Atrin’s lead product is ATRN-119, a novel, potentially best-in-class small molecule ATR inhibitor. Atrin plans to initiate a first-in-human trial for ATRN-119 in early 2020.